This course is based on reading and discussing primary literature that
exemplifies approaches that have revealed new concepts and principles
governing biological systems. Special emphasis will be placed on
difficulties that lie at the interface of theory and experiment in
bioengineering and systems biology. Each week, the students will read
and discuss two important papers, and the majority of the class time
will be devoted to student discussions rather than to formal lectures.
Topics include: cooperativity, robust adaptation, kinetic
proofreading, sequence analysis, clustering, network analysis,
dynamical systems, and biological design principles.